There is no shortage of excitement on today’s MLB schedule, including the Arizona Diamondbacks playing the Milwaukee Brewers.

Take a peek at our betting breakdown for the MLB’s action today.

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MLB Betting Info Today – Sept. 22

Minnesota Twins (81-73) at Boston Red Sox (76-78)

Betting Info & Picks

• Moneyline Favorite: Red Sox -125
• Moneyline Underdog: Twins +105
• Total: 7.5 Runs (-110 to go over, -110 to go under)
• Prediction: Red Sox 5, Twins 4
• Moneyline Pick: Red Sox (105) over the Twins (-125)
• Total Pick: Over 7.5 Runs

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How to Watch

• TV Channel: BSN
• Live Stream: Watch on Fubo (Regional restrictions may apply)
• Game Time: 12:35 PM ET
• Venue: Fenway Park
• Location: Boston, Massachusetts
• Red Sox Starter: Nick Pivetta (5-11, 4.37 ERA)
• Twins Starter: Pablo Lopez (15-8, 3.84 ERA)

Pittsburgh Pirates (72-83) at Cincinnati Reds (76-80)

Betting Info & Picks

• Moneyline Favorite: Reds -120
• Moneyline Underdog: Pirates +100
• Total: 8 Runs (-110 to go over, -110 to go under)
• Prediction: Reds 5, Pirates 4
• Moneyline Pick: Reds (100) over the Pirates (-120)
• Total Pick: Over 8 Runs

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How to Watch

• TV Channel: SportsNet PT
• Live Stream: Watch on Fubo (Regional restrictions may apply)
• Game Time: 1:10 PM ET
• Venue: Great American Ball Park
• Location: Cincinnati, Ohio
• Reds Starter: Hunter Greene (9-4, 2.83 ERA)
• Pirates Starter: Paul Skenes (10-3, 2.07 ERA)

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Detroit Tigers (81-74) at Baltimore Orioles (86-69)

Betting Info & Picks

• Moneyline Favorite: Orioles
• Moneyline Underdog: Tigers
• Total: Runs ( to go over, to go under)
• Prediction: Orioles 5, Tigers 4
• Moneyline Pick: Orioles () over the Tigers ()

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How to Watch

• TV Channel: MASN
• Live Stream: Watch on Fubo (Regional restrictions may apply)
• Game Time: 1:35 PM ET
• Venue: Oriole Park at Camden Yards
• Location: Baltimore, Maryland
• Orioles Starter: Albert Suarez (8-6, 3.6 ERA)
• Tigers Starter: Casey Mize (2-6, 4.36 ERA)

Toronto Blue Jays (73-82) at Tampa Bay Rays (77-78)

Betting Info & Picks

• Moneyline Favorite: Rays
• Moneyline Underdog: Blue Jays
• Total: Runs ( to go over, to go under)
• Prediction: Rays 4, Blue Jays 3
• Moneyline Pick: Rays () over the Blue Jays ()

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How to Watch

• TV Channel: BSSUN
• Live Stream: Watch on Fubo (Regional restrictions may apply)
• Game Time: 1:40 PM ET
• Venue: Tropicana Field
• Location: St. Petersburg, Florida
• Rays Starter: Shane Baz (3-3, 3.21 ERA)
• Blue Jays Starter: Chris Bassitt (10-13, 4.16 ERA)

Atlanta Braves (84-71) at Miami Marlins (57-98)

Betting Info & Picks

• Moneyline Favorite: Braves -200
• Moneyline Underdog: Marlins +165
• Total: 8.5 Runs (-125 to go over, +105 to go under)
• Prediction: Braves 6, Marlins 5
• Moneyline Pick: Braves (-200) over the Marlins (+165)
• Total Pick: Over 8.5 Runs

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How to Watch

• TV Channel: MLB Network
• Live Stream: Watch on Fubo (Regional restrictions may apply)
• Game Time: 1:40 PM ET
• Venue: LoanDepot park
• Location: Miami, Florida
• Marlins Starter: Darren McCaughan (0-0, 7.64 ERA)
• Braves Starter: Grant Holmes (2-1, 3.84 ERA)

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Los Angeles Angels (62-93) at Houston Astros (85-70)

Betting Info & Picks

• Moneyline Favorite: Astros -275
• Moneyline Underdog: Angels +220
• Total: 8.5 Runs (-110 to go over, -110 to go under)
• Prediction: Astros 5, Angels 4
• Moneyline Pick: Astros (-275) over the Angels (+220)
• Total Pick: Over 8.5 Runs

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How to Watch

• TV Channel: BSW
• Live Stream: Watch on Fubo (Regional restrictions may apply)
• Game Time: 2:10 PM ET
• Venue: Minute Maid Park
• Location: Houston, Texas
• Astros Starter: Spencer Arrighetti (7-13, 4.68 ERA)
• Angels Starter: Griffin Canning (6-13, 5.21 ERA)

San Francisco Giants (76-79) at Kansas City Royals (82-73)

Betting Info & Picks

• Moneyline Favorite: Royals -115
• Moneyline Underdog: Giants -105
• Total: 7.5 Runs (+100 to go over, -120 to go under)
• Prediction: Royals 5, Giants 4
• Moneyline Pick: Royals (-105) over the Giants (-115)
• Total Pick: Over 7.5 Runs

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How to Watch

• TV Channel: BSKC
• Live Stream: Watch on Fubo (Regional restrictions may apply)
• Game Time: 2:10 PM ET
• Venue: Kauffman Stadium
• Location: Kansas City, Missouri
• Royals Starter: Seth Lugo (16-8, 3.05 ERA)
• Giants Starter: Blake Snell (4-3, 3.31 ERA)

Arizona Diamondbacks (87-68) at Milwaukee Brewers (88-67)

Betting Info & Picks

• Moneyline Favorite: Brewers -120
• Moneyline Underdog: Diamondbacks +100
• Total: 8.5 Runs (-120 to go over, +100 to go under)
• Prediction: Brewers 5, Diamondbacks 4
• Moneyline Pick: Brewers (-120) over the Diamondbacks (+100)
• Total Pick: Over 8.5 Runs

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How to Watch

• TV Channel: BSWI
• Live Stream: Watch on Fubo (Regional restrictions may apply)
• Game Time: 2:10 PM ET
• Venue: American Family Field
• Location: Milwaukee, Wisconsin
• Brewers Starter: Frankie Montás (7-11, 4.5 ERA)
• Diamondbacks Starter: Jordan Montgomery (8-7, 6.23 ERA)

Cleveland Guardians (90-66) at St. Louis Cardinals (78-77)

Betting Info & Picks

• Moneyline Favorite: Cardinals -115
• Moneyline Underdog: Guardians -105
• Total: 7.5 Runs (-115 to go over, -105 to go under)
• Prediction: Cardinals 5, Guardians 4
• Moneyline Pick: Cardinals (-105) over the Guardians (-115)
• Total Pick: Over 7.5 Runs

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How to Watch

• TV Channel: BSGL
• Live Stream: Watch on Fubo (Regional restrictions may apply)
• Game Time: 2:15 PM ET
• Venue: Busch Stadium
• Location: St. Louis, Missouri
• Cardinals Starter: Andre Pallante (7-8, 3.87 ERA)
• Guardians Starter: Gavin Williams (3-10, 5.12 ERA)

Washington Nationals (69-86) at Chicago Cubs (79-76)

Betting Info & Picks

• Moneyline Favorite: Cubs -190
• Moneyline Underdog: Nationals +155
• Total: 7.5 Runs (-115 to go over, -105 to go under)
• Prediction: Cubs 4, Nationals 3
• Moneyline Pick: Cubs (-190) over the Nationals (+155)
• Total Pick: Under 7.5 Runs

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How to Watch

• TV Channel: MARQ
• Live Stream: Watch on Fubo (Regional restrictions may apply)
• Game Time: 2:20 PM ET
• Venue: Wrigley Field
• Location: Chicago, Illinois
• Cubs Starter: Shota Imanaga (14-3, 3.03 ERA)
• Nationals Starter: Jake Irvin (10-12, 4.07 ERA)

Seattle Mariners (80-75) at Texas Rangers (73-82)

Betting Info & Picks

• Moneyline Favorite: Mariners -125
• Moneyline Underdog: Rangers +105
• Total: 8 Runs (-105 to go over, -115 to go under)
• Prediction: Mariners 5, Rangers 4
• Moneyline Pick: Mariners (-125) over the Rangers (+105)
• Total Pick: Over 8 Runs

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How to Watch

• TV Channel: BSSW
• Live Stream: Watch on Fubo (Regional restrictions may apply)
• Game Time: 2:35 PM ET
• Venue: Globe Life Field
• Location: Arlington, Texas
• Rangers Starter: Andrew Heaney (5-14, 3.89 ERA)
• Mariners Starter: Bryan Woo (8-3, 2.85 ERA)

New York Yankees (90-64) at Oakland Athletics (67-87)

Betting Info & Picks

• Moneyline Favorite: Yankees -185
• Moneyline Underdog: Athletics +150
• Total: 8.5 Runs (-110 to go over, -110 to go under)
• Prediction: Yankees 6, Athletics 5
• Moneyline Pick: Yankees (-185) over the Athletics (+150)
• Total Pick: Over 8.5 Runs

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How to Watch

• TV Channel: NBCS-CA
• Live Stream: Watch on Fubo (Regional restrictions may apply)
• Game Time: 4:07 PM ET
• Venue: Oakland-Alameda County Coliseum
• Location: Oakland, California
• Athletics Starter: Joey Estes (7-8, 4.78 ERA)
• Yankees Starter: Luis Gil (14-6, 3.14 ERA)

Colorado Rockies (59-95) at Los Angeles Dodgers (92-62)

Betting Info & Picks

• Moneyline Favorite: Dodgers -350
• Moneyline Underdog: Rockies +280
• Total: 8.5 Runs (-105 to go over, -115 to go under)
• Prediction: Dodgers 5, Rockies 3
• Moneyline Pick: Dodgers (-350) over the Rockies (+280)
• Total Pick: Under 8.5 Runs

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How to Watch

• TV Channel: COLR
• Live Stream: Watch on Fubo (Regional restrictions may apply)
• Game Time: 4:10 PM ET
• Venue: Dodger Stadium
• Location: Los Angeles, California
• Dodgers Starter: Yoshinobu Yamamoto (6-2, 2.63 ERA)
• Rockies Starter: Antonio Senzatela (0-0, 6 ERA)

Chicago White Sox (36-118) at San Diego Padres (88-66)

Betting Info & Picks

• Moneyline Favorite: Padres -300
• Moneyline Underdog: White Sox +240
• Total: 7.5 Runs (-115 to go over, -105 to go under)
• Prediction: Padres 5, White Sox 3
• Moneyline Pick: Padres (-300) over the White Sox (+240)
• Total Pick: Over 7.5 Runs

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How to Watch

• TV Channel: SDPA
• Live Stream: Watch on Fubo (Regional restrictions may apply)
• Game Time: 4:10 PM ET
• Venue: PETCO Park
• Location: San Diego, California
• Padres Starter: Yu Darvish (6-3, 3.21 ERA)
• White Sox Starter: Sean Burke (1-0, 2.25 ERA)

Minnesota Twins (81-73) at Boston Red Sox (76-78)

Betting Info & Picks

• Moneyline Favorite: Red Sox -110
• Moneyline Underdog: Twins -110
• Total: 8 Runs (-110 to go over, -110 to go under)
• Prediction: Red Sox 6, Twins 5
• Moneyline Pick: Red Sox (-110) over the Twins (-110)
• Total Pick: Over 8 Runs

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How to Watch

• TV Channel: BSN
• Live Stream: Watch on Fubo (Regional restrictions may apply)
• Game Time: 5:35 PM ET
• Venue: Fenway Park
• Location: Boston, Massachusetts
• Red Sox Starter: Kutter Crawford (8-15, 4.19 ERA)
• Twins Starter: Zebby Matthews (1-3, 6.3 ERA)

Philadelphia Phillies (92-63) at New York Mets (86-69)

Betting Info & Picks

• Moneyline Favorite: Mets -160
• Moneyline Underdog: Phillies +135
• Total: 6.5 Runs (-125 to go over, +105 to go under)
• Prediction: Mets 5, Phillies 4
• Moneyline Pick: Mets (135) over the Phillies (-160)
• Total Pick: Over 6.5 Runs

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How to Watch

• TV Channel: ESPN
• Live Stream: Watch on Fubo (Regional restrictions may apply)
• Game Time: 7:15 PM ET
• Venue: Citi Field
• Location: Queens, New York
• Mets Starter: Tylor Megill (4-5, 4.08 ERA)
• Phillies Starter: Zack Wheeler (16-6, 2.56 ERA)

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