When the No. 22 Louisville Cardinals square off against the Jacksonville State Gamecocks at 3:30 p.m. ET on Saturday, Sept. 7, our computer model predicts the Cardinals will take home the win. Our model also projects the spead, point total, and final score, which you can read below.

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Jacksonville State vs. Louisville Predictions and Picks

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Jacksonville State Betting Info (2024)

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• Sportsbooks have implied with the moneyline set for this matchup that the Gamecocks have a 5.3% chance to win.
• The Gamecocks have put together a 0-1-0 record against the spread this season.
• Out of Gamecocks one games with a set total, all have hit the over.
• The average total in Jacksonville State games this year is two less points than the point total of 56.5 for this outing.

Louisville Betting Info (2023)

• The Cardinals have a 98.5% chance to win this matchup based on the moneyline’s implied probability.
• The Cardinals went 6-7-1 ATS last season.
• Louisville did not lose ATS (1-0) as a 28.5-point or greater favorite last year.
• Cardinals games hit the over seven out of 14 times last season.
• The over/under for this game is 56.5 points, 6.1 more than the average point total for Louisville games a year ago.

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Gamecocks vs. Cardinals 2024 Scoring Averages

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